Thématiques de Recherche
- Intoxications par biotoxines marines (ciguatéra)
- Veille scientifique et technologique des méthodes de détection
- Développement et implantation de méthodes de détection des toxines de la Ciguatéra, les ciguatoxines (CTXs), et les toxines marines associées (Saxitoxines, Acide Okadaïque, Palytoxines, Azaspiracides, etc…) dans le phytobenthos et les produits de la mer susceptibles d’être contaminés
- Test interaction ligand-récepteur http://www.ilm.pf/Testbinding
- Test de cytotoxicité sur neuroblastome de souris (N2a)
- Amélioration des connaissances de la chaîne trophique de la ciguatéra
- Evaluation et gestion du risque ciguatérique dans les lagons de Polynésie : sécurisation des filières de pêche lagonaire, cartographie des zones et espèces à risque, information et sensibilisation des populations.
Liens web
https://www.ilm.pf/recherche/biotoxines-marines/
https://www.ciguatera.pf/index.php/fr/
https://publons.com/researcher/2376709/helene-taiana-darius/
http://orcid.org/0000-0002-1184-7034
Autres responsabilités administratives et scientifiques
2019-2022 : Membre du comité éditorial du journal Marine Drugs (IF 2020 5.118)
2021-2022 : Éditeur invité du numéro spécial “Development and Application of Specific Binding Assays for Marine Toxins” du journal Marine Drugs (IF 5.118)
https://www.mdpi.com/journal/marinedrugs/special_issues/marinetoxins_analysis
Publications
2022
ACL
Darius, H.T., Revel, T., Viallon, J., Sibat, M., Cruchet, P., Longo, S., Hardison, D.R, Holland, W.C., Tester, P.A., Litaker, R.W., McCall, J.R., Hess, P., Chinain, M., 2022. Comparative study on the performance of three detection methods for the quantification of Pacific ciguatoxins in French Polynesian strains of Gambierdiscus polynesiensis. Marine Drugs, 20(6), 348, https://doi.org/10.3390/md20060348, WOS: (IF: 5.118)
Darius, H.T., Paillon, C., Mou-Tham G., Ung, A., Cruchet, P., Revel, T., Viallon, J., Vigliola, L., Ponton, D., Chinain, M. 2022. Evaluating age and growth relationship to ciguatoxicity in five coral reef fish species from French Polynesia. Marine Drugs, 20(4) 251, https://doi.org/10.3390/md20040251; WOS: (IF: 5.118)
2021
ACL
Chinain, M., Gatti, C.M.i, Darius, H.T., Quod, J-P., Tester, P.A. 2021. Ciguatera poisonings: A global review of occurrences and trends. Harmful algae, 102, 101873, https://doi.org/10.1016/j.hal.2020.101873; WOS:000641459100005 (IF: 4.273)
Darius, H.T., Revel, T., Cruchet, P., Viallon, J., Sibat, M., Hess, P., Chinain, M. 2021. Deep-water fish are potential vectors of Ciguatera poisoning in the Gambier Islands, French Polynesia. Marine Drugs, 19(11), 644, https://doi.org/10.3390/md19110644; WOS: 000727087400001 (IF: 5.118)
Leite, I. Do Prado, Sdiri K., Taylor A., Viallon J., Gharbia, H.B., Mafra Jr L.L., Swarzenski, P., Oberhaensli, F.R., Darius H.T., Chinain M., Dechraoui Bottein M.Y. 2021. Experimental evidence of ciguatoxin accumulation and depuration in carnivorous lionfish. Toxins https://doi.org/10.3390/toxins13080564; WOS:000690137800001 (IF: 4.546)
CO
Chinain M., Gatti C., Martin-Yken, H., Roué M., Darius H.T. Ciguatera poisoning: an increasing burden for Pacific Island communities in light of climate change. In: Climate change and marine and freshwater toxins, 2nd edition, Botana, L.M., Louazo, M.C., Vilarino, N., eds., Walter de Gruyter GmbH, Berlin, Boston, Chapter 10, 369-428. ISBN 978-3-11-062292-8
C-ACTI
Chinain M, Gatti CMi, Darius HT, Quod JP, Tester PA. (2021). Ciguatera Poisonings: a global review of occurrences and trends. Global HAB Status Report Initiative Launching Webinar, 15 June 2021, IOC-UNESCO; https://www.youtube.com/watch?v=kvDxVFVHEf0
Chinain M, Gatti CMi, Darius HT, Quod JP, Tester PA. (2021). Global occurrences and trends of Ciguatera Poisoning. 19th International Conference on Harmful Algae, 10-15 October 2021, La Paz, Mexico
2020
ACL
Chinain, M., Gatti, C.M.i, Ung, A., Cruchet, P., Revel, T., Viallon, J., Sibat, M., Varney, P., Laurent, V., Hess, P., Darius, H.T. 2020. Evidence for the Range Expansion of Ciguatera in French Polynesia: A Revisit of the 2009 Mass-Poisoning Outbreak in Rapa Island (Australes Archipelago). Toxins, 12(12), 759, https://doi.org/10.3390/toxins12120759; WOS:000602320400001 (IF: 4.546)
Chomérat N., Bilien G., Viallon J., Hervé F., Réveillon D., Henry K., Zubia M., Viera C., Ung A., Gatti C.M., Roué M., Derrien A., Amzil Z., Darius H.T., Chinain M. 2020. Taxonomy and toxicity of a bloom-forming Ostreopsis species (Dinophyceae, Gonyaulacales) in Tahiti island (South Pacific Ocean): one step further towards resolving the identity of O. siamensis. Harmful Algae, (1) 98. https://doi.org/10.1016/j.hal.2020.101888; WOS:000583196800005 (IF: 4.273)
Longo, S., Sibat, M., Darius, H.T., Hess, P., Chinain, M. 2020. Effects of pH and nitrogen nutrients on growth and toxin profiles of the ciguatera-causing dinoflagellate Gambierdiscus polynesiensis (Dinophyceae) Toxins, 12(12), 767, https://doi.org/10.3390/toxins12120767; WOS:000602428800001 (IF: 4.546)
Roué, M., Smith, K.F., Sibat, M., Viallon, J., Henry, K., Ung, A., Biessy, L., Hess, P., Darius, H.T., Chinain, M. 2020. Assessment of ciguatera and other phycotoxin-related risks in Anaho Bay (Nuku Hiva Island, French Polynesia): Molecular, toxicological, and chemical analyses of passive samplers. Toxins, 12 (5), 321. https://doi.org/10.3390/toxins12050321; WOS:000541799400042 (IF: 4.546)
Viallon, J., Chinain, M., Darius, H.T. 2020. Revisiting the neuroblastoma cell-based assay (CBA-N2a) for the improved detection of marine toxins active on voltage gated sodium channels (VGSCs). Toxins, 12 (5), 281. https://doi.org/10.3390/toxins12050281 ; WOS:000541799400053 (IF: 4.546)
ASCL
Chomérat, N., Bilien, G., Réveillon, D., Hervé F., Viallon J., Darius H.T., Chinain M. 2020. New insights on the diversity of the dinoflagellate genus Ostreopsis in lagoons of French Polynesia, South Pacific Ocean. Harmful Algal News, 65: 8-9. http://www.e-pages.dk/ku/1481
CO
Chinain M., Gatti C., Roué M., Darius H.T. Ciguatera-causing dinoflagellates in the genera Gambierdiscus and Fukuyo: Distribution, ecophysiology and toxicology. In: Dinoflagellates: Classification, Evolution, Physiology and Ecological Significance, Subba Rao, D.V, ed., The Nova Science Publishers, New-York, Chapter 11, 405-457. ISBN 978-1-53617-888-3
2019
ACL
Chomérat N., Bilien G., Derrien A., Henry K., Ung A., Viallon J., Darius H.T., Gatti C.M., Roué M., Hervé F., Réveillon D., Amzil Z., Chinain M. 2019. Ostreopsis lenticularis Y. Fukuyo (Dinophyceae, Gonyaulacales) from French Polynesia (South Pacific Ocean): a revisit of its morphology, molecular phylogeny and toxicity. Harmful Algae, 84: 95-111. https://doi.org/10.1016/j.hal.2019.02.004; WOS:000471087800011 (IF: 3.707)
Longo, S., Sibat, M., Viallon, J., Darius, H.T., Hess, P., Chinain, M. 2019. Intraspecific variability in the toxin production and toxin profiles of in vitro cultures of Gambierdiscus polynesiensis (Dinophyceae) from French Polynesia. Toxins, 11 (12), 735. https://doi.org/10.3390/toxins11120735; WOS:000507337800058 (IF: 3.531)
Rodier M., Longo S., Henry K., Ung A., Lo-Yat A., Darius H.T., Viallon J., Beker B., Delesalle B., Chinain M. 2019. Diversity and toxic potential of algal bloom forming species from Takaroa atoll lagoon (Tuamotu, French Polynesia): a field and mesocosm study. Aquatic Microbial Ecology, 83(1): 15-34. https://doi.org/10.3354/ame01900; WOS:000487114800002 (IF: 1.841)
ACLN
Chinain M., Gatti C., Roué M., Darius H.T. 2019. Ciguatera Poisoning: insights into the novel trends of an ancient disease. New Microbes and New Infections, https://doi.org/10.1016/j.nmni.2019.100565.
2018
ACL
Sibat M., Herrenknechtb C., Darius H.T., Roué M., Chinain M., Hess P. 2018. Detection of pacific ciguatoxins using liquid chromatography coupled to either low or high resolution mass spectrometry (LC-MS/MS). Journal of Chromatography A, 1571: 16–28. https://doi.org/10.1016/j.chroma.2018.08.008, WOS:000446284600002 (IF: 3.858)
Clausing R.J., Losen B., Oberhaensli F.R., Darius H.T., Sibat M., Hess P., Swarzenski P.W., Amzil, Z., Chinain M., Dechraoui Bottein M-Y. 2018. Experimental evidence of dietary ciguatoxin accumulation in an herbivorous coral reef fish. Aquatic Toxicology, 200: 257-265. https://doi.org/10.1016/j.aquatox.2018.05.007, WOS:000438180700027 (IF: 3.794)
Roué M., Darius H.T., Ung, A., Viallon J., Sibat M., Amzil Z., Chinain M. 2018. Tissue distribution and detoxification of ciguatoxins in giant clam Tridacna maxima experimentally fed with Gambierdiscus polynesiensis. Toxins, 10(5): 189. https://doi.org/10.3390/toxins10050189, WOS:000435198800020
Roué M., Darius H.T., Chinain M. 2018. Solid Phase Adsorption Toxin Tracking (SPATT) Technology for the Monitoring of Aquatic Toxins: A Review. Toxins, 10(4): 167. https://doi.org/10.3390/toxins10040167, WOS:000435183700038 (IF: 3.895)
Darius H.T., Roué M., Sibat M., Viallon J., Gatti C.M., Vandersea M.K., Tester P.A., Litaker R.W., Amzil Z., Hess P., Chinain M. 2018. Toxicological investigations on the sea urchin Tripneustes gratilla (Toxopneustidae, Echinoid) from Anaho Bay (Nuku Hiva, French Polynesia): evidence for the presence of Pacific ciguatoxins. Marine Drugs, 16(4): 122. https://doi.org/10.3390/md16040122, WOS:000431068000024 (IF: 3.772)
Martin-Yken H., Derick S., Gironde C., Darius H.T., Furger C., Laurent D., Chinain M. 2018. Ciguatoxins activate the Calcineurin signalling pathway in Yeasts: potential for development of an alternative detection tool. Environmental Research, 162: 144-151. https://doi.org/10.1016/j.envres.2017.12.022, WOS:000426325300017 (IF: 5.051)
Gatti C.M., Lonati D., Darius H.T., Zancan A., Roué M., Amzil Z., Locatelli C.A., Chinain M. 2018. Tectus niloticus (Tegulidae, Gastropod) as a novel vector of Ciguatera Shellfish Poisoning: Clinical characterization and follow up of a mass poisoning event in Nuku Hiva island (Marquesas, French Polynesia). Toxins, 10(3): 102. https://doi.org/10.3390/toxins10030102, WOS:000428565500010 (IF: 3.895)
Roué M., Darius H.T., Viallon J., Ung A., Gatti C., Harwood T., Chinain M. 2018. Application of Solid Phase Adsorption Tracking (SPATT) devices for the field detection of Gambierdiscus toxins. Harmful Algae, 71: 40-49. https://doi.org/10.1016/j.hal.2017.11.006, WOS:000423890200005 (IF: 5.012)
Darius H.T., Roué M., Sibat M., Viallon J., Gatti C.M., Vandersea M.K., Tester P.A., Litaker R.W., Amzil Z., Hess P., Chinain M. 2018. Tectus niloticus (Tegulidae, Gastropod) as a novel vector of Ciguatera Poisoning: Detection of Pacific ciguatoxins in toxic samples from Nuku Hiva Island (French Polynesia). Toxins, 10(1): 2. https://doi.org/10.3390/toxins10010002, WOS:000424096500002 (IF: 3.895)
Hardison DR., Holland W.C., Darius H.T., Chinain M., Tester P.A., Shea D., Bogdanoff, A.K., Morris J.A. Jr, Flores Quintana H.A., Loeffer, C.R., Buddo, D., Litaker R.W. 2018. Investigation of ciguatoxins in invasive Lionfish from the greater Caribbean region: implications for fishery development. PLoS ONE, 13(6): e0198358. https://doi.org/10.1371/journal.pone.0198353, WOS:000435655600019 (IF: 2,776)
ASCL
Darius H.T., Roué M., Sibat M., Viallon J., Gatti C.M., Vandersea M.K., Tester P.A., Litaker R.W., Amzil Z., Hess P., Chinain M. 2018. Contribution of marine invertebrates to Ciguatera poisoning: the case study of French Polynesia. Harmful Algal News, 60: 6-7. http://www.e-pages.dk/ku/1380/
Roué M., Darius H.T., Gatti C.M., Chinain M., Harwood T. 2018. Solid phase adsorption toxin tracking (SPATT) technology for field monitoring of Gambierdiscus toxins with passive samplers. Harmful Algal News, 60: 8-9. http://www.e-pages.dk/ku/1380/
C-ACTI
Darius H.T., Roué M., Sibat M., Viallon J., Gatti C.M., Vandersea M.K., Tester P.A., Litaker R.W., Amzil Z., Hess P., Chinain M. 2018. Contribution of marine invertebrates in ciguatera phenomenon. The 18th International Conference on Harmful Algae, Nantes, France, 22-26 Octobre 2018.
Roué M., Darius H.T., Viallon J., Ung A., Gatti C.M., Sibat M., Harwood T., Hess P., Chinain M. 2018. Solid Phase Adsorption Toxin Tracking (SPATT) technology as a useful tool for the passive field-monitoring of Gambierdiscus toxins. The 18th International Conference on Harmful Algae, Nantes, France, 22-26 Octobre 2018
C-COM
Martin-Yken H., Gironde C., Darius H.T., Furger C., Trevisiol E., Chinain M., Dague E. New strategies in the fight against Ciguatera. NANOinBIO 2018 Conference, Guadeloupe, 22-27 Mai 2018
2017
C-ACTI
Darius H.T., Revel T., Viallon J., McCall J.R., Hardison D.R., Holland W.C., Tester P.A., Litaker R.W., Chinain M. 2017. Applicability of the fluorescent Receptor Binding Assay (RBAF) to the detection of Ciguatoxins in Pacific reef fish. 10th Indo-Pacific Fish Conference, Tahiti, Polynésie française, 2-6 Octobre 2017.
Chinain M., Gatti C., Dechraoui-Bottein M.Y., Darius H.T. 2017. Effects of ciguatoxins accumulation in fish. 10th Indo-Pacific Fish Conference, Tahiti, Polynésie française, 2-6 Octobre 2017.
Roué M., Darius H.T., Viallon J., Ung A., Gatti C., Harwood D.T., Chinain M. 2017. Application of Solid Phase Adsorption Toxin Tracking (SPATT) devices for an improved Ciguatera Fish Poisoning (CFP) risk assessment. 10th Indo-Pacific Fish Conference, Tahiti, Polynésie française, 2-6 Octobre 2017.
Clausing R., Losen B., Oberhaensli F., Darius H.T., Sibat M., Hess P., Chinain M., Dechraoui-Bottein M.Y. 2017. Experimental evidence of ciguatoxin continued bioaccumulation in an herbivorous coral reef fish. 10th Indo-Pacific Fish Conference, Tahiti, Polynésie française, 2-6 Octobre 2017.
Murray S., Harwood D.T., Darius H.T., Viallon J., Rhodes L., Smith K., Munday R., Chinain M. 2017. Understanding the complexities associated with the chemical analysis of ciguatoxins. 10th Indo-Pacific Fish Conference, Tahiti, Polynésie française, 2-6 Octobre 2017.
Smith K., Rhodes L., Verma A., Curley B., Kohli G., Kretzschmar A.L., Harwood D.T., Murray S., Rongo T., Darius H.T., Viallon J., Chinain M., Murray S. 2017. Distribution and diversity of Gambierdiscus spp. and associated levels of ciguatoxins in herbivorous fish from a ciguatera-endemic area in the Cook Islands. 10th Indo-Pacific Fish Conference, Tahiti, Polynésie française, 2-6 Octobre 2017
C-COM
Chinain M, Longo S, Henry K, Ung A, Darius HT, Viallon J, Rodier M, Delesalle B, Lo-Yat A, Le Moullac G, Araoz R. (2017). Microalgae from French Polynesian lagoons: novel source of bioactive compounds? Journées nationales de rencontre du GDR PHYCOTOX & GIS CYANO. CNRS, Gif-sur-Yvette France, 14- 16 Mars 2017.
Chomérat N, Gatti C, Bilien G, Ung A, Darius HT, Litaker RW, Tester PA, Chinain M. (2017). Taxonomic diversity of the dinoflagellate genus Ostreopsis in French Polynesia: preliminary results from Marquesas Islands (Pacific Ocean). Journées nationales de rencontre du GDR PHYCOTOX & GIS CYANO. CNRS, Gif-sur-Yvette France, 14- 16 Mars 2017.
Clausing R, Losen B, Darius HT, Hess P, Sibat M, Viallon J, Chinain M, Dechraoui Bottein M-Y. (2017). Continued feeding with Gambierdiscus polynesiensis causes increasing accumulation of ciguatoxin over 16 weeks in an herbivorous reef fish. Journées nationales de rencontre du GDR PHYCOTOX & GIS CYANO. CNRS, Gif-sur-Yvette France, 14- 16 Mars 2017.
Darius HT, Viallon J, Mc Call J, Revel T, Hardison DR, Holland WC, Tester PA, Litaker RW, Chinain M. (2017). Latest advances in two functional methods to detect ciguatoxins (CTXs): the Receptor Binding Assay (RBA) and the Cell Based Assay (CBA-N2a). Journées nationales de rencontre du GDR PHYCOTOX & GIS CYANO. CNRS, Gif-sur-Yvette France, 14- 16 Mars 2017.
2016
ACL
Hardison DR, Holland WC, McCall JR, Bourdelais AJ, Baden DG, Darius HT, Chinain M, Tester PA, Shea D, Flores QuintanaHA, Morris Jr. JA, Litaker RW. (2016). Fluorescent Receptor Binding Assay for detecting ciguatoxins in fish. PLoS ONE, 11(4): e0153348, https://doi.org/10.1371/journal.pone.0153348, WOS:000374131200077 (IF: 2.806)
Roué M, Darius HT, Picot S, Ung A, Viallon J, Gaertner-Mazouni N, Sibat M, Amzil Z, Chinain M. (2016). First evidence of the bioaccumulation of ciguatoxins in giant clams (Tridacna maxima) exposed to Gambierdiscus spp. cells. Harmful Algae, 57: 78-87. https://doi.org/10.1016/j.hal.2016.05.007, WOS:000381544600008 (IF: 3.087)
ASCL
Roué M., Darius H.T., Chinain M., Sibat M., Amzil Z. 2016. Ability of giant clams to bio-accumulate ciguatoxins from Gambierdiscus cells. Harmful Algal News, 55: 12-13 http://www.e-pages.dk/ku/1259/ PV
Chinain M., Darius H.T., Gatti C., Roué M. 2016. Update on ciguatera research in French Polynesia. SPC Fisheries Newsletter, 150: 42-51. (http://purl.org/spc/digilib/doc/yuim2 )
2015
ASCL
Gatti C, Darius HT, Chinain M, Lonati D. (2015). First report of a mass-poisoning outbreak following the consumption of Tectus niloticus (Gastropod) in French Polynesia: a novel pathway of Ciguatera Fish Poisoning? IOC newsletter on Toxic Algae and Algal Blooms, n°50, January 2015, http://www.e-pages.dk/ku/1086/
C-ACTI
Dechraoui Bottein M-Y., Tabadda R.S., Chinain M., Darius H.T., Amaya O., Porntepkasemsan B., Romarin M., Tester P.A., Enevoldsen H., Van Dolah F.M. 2015. Linking nuclear science and seafood safety: Reliability of the receptor binding assay for PSP and ciguatera toxins. 8th US HAB Symposia, Long Beach, CA, USA, 15-19 Novembre 2015.
Lonati D., Gatti C., Zancan A., Darius H.T., Fleure M., Chinain M., Buonocore M., Locatelli C.A. Novel Ciguatera shellfish poisoning (CSP) cluster after consumption of Tectus niloticus, a gastropod, in Nuku Hiva, French Polynesia. 35th International Congress of the European Association of Poisons Centers and Clinical Toxicologists (EAPCCT), Malte, Clinical Toxicology 53(4): 278. 26-29 Mai 2015. WOS:000351927300104
C-COM
Gatti C, Darius HT, Roué M, Lonati D, Sibat-Dubois M, Savar V, Amzil Z, Chinain M. 2015. Novel case report of a Ciguatera Shellfish Poisoning cluster following the consumption of Tectus niloticus (Gastropod) in French Polynesia. AG du GDR Phycotox, 31 mars-02 avril 2015, Brest, France.
Darius H.T. Detection tests for ciguatoxins (CTXs). 2nd coordination Meeting RAS7026 Project – Atelier régional sur la ciguatera AIEA, IOC, NOAA, ILM, Tahiti, 2-13 Mars 2015.
2014
ACL
Pawlowiez R, Morey JS, Darius HT, Chinain M, Van Dolah FM. (2014). Transcriptome sequencing reveals single domain type I-like Polyketide Synthases in the toxic dinoflagellate Gambierdiscus polynesiensis. Harmful Algae, 36 : 29-37. https://doi.org/10.1016/j.hal.2014.04.013, WOS:000338622500004 (IF: 3,339)
Gaboriau M, Ponton D, Darius HT, Chinain M. (2014). Ciguatera fish toxicity in French Polynesia: size does not always matter. Toxicon, 84 : 41-50. https://doi.org/10.1016/j.toxicon.2014.03.006, WOS:000336706600006 (IF: 2,492)
ACLN
Chinain M, Gatti C, Roué M, Laurent D, Darius HT. 2014. Ciguatéra : aspects écologiques, biologiques et toxicologiques. Revue Francophone des Laboratoires 460 :27-39. https://doi.org/10.1016/S1773-035X(14)72403-7
C-ACTI
Chinain M., Gatti C.M., Roué M., Darius H.T. 2014. Integrated study of a fish poisoning outbreak in Rapa (Australes, French Polynesia). The 16th International Conference on Harmful Algae, Wellington, New Zealand, 27-31 October 2014
Gatti C.M., Darius H.T., Ponzo N., Sevrain Hiribarren B., Chinain M. 2014. Ciguatera 2.0: A website as a helpful tool to improve ciguatera surveillance, risk management and research advances. The 16th International Conference on Harmful Algae, Wellington, New Zealand, 27-31 October 2014..
Roué M., Picot S., Ung A., Viallon J., Sibat M., Amzil Z., Gaertner-Mazouni N., Chinain M., Darius H.T. 2014. Giant clams: could they represent a new vector of Ciguatera? The 16th International Conference on Harmful Algae, Wellington, New Zealand, 27-31 October 2014.
C-AFF
Roué M, Ung A, Darius HT, Harwood T, Chinain M. (2014). Evaluation of Solid-Phase Adsorption Toxin Tracking devices for the monitoring of Ciguatera. 16th International Conference on Harmful Algae, 27-31 octobre 2014, Wellington, Nouvelle-Zélande.
Darius HT, Roué M, Ung A, Cruchet P, Revel T, Viallon J, Suhas E, Gatti C, Chinain M. (2014). Ecotoxicological characterization of 3 different lagoons of French Polynesia: Tikehau, Kaukura and Mangareva. 16th International Conference on Harmful Algae, 27-31 octobre 2014, Wellington, Nouvelle-Zélande.
2013
ACL
Darius HT, Drescher O, Ponton D, Pawlowiez R, Laurent D, Dewailly E, Chinain M. (2013). Use of traditional tests to detect ciguateric fish: a scientific evaluation of their effectiveness in Raivavae Island (Australes, French Polynesia). Food Additives and Contaminants, Part A, 30(3): 550-556. https://doi.org/10.1080/19440049.2012.752581, WOS:000327813300014 (IF : 2.22)
Pawlowiez R, Darius HT, Cruchet P, Rossi F, Caillaud A, Laurent D, Chinain M. (2013). Sanitary risk associated with seafood consumption in the Australes archipelago (French Polynesia), as assessed by the neuroblastoma cell based assay (Neuro-2a CBA). Food Additives and Contaminants, Part A, 30(3): 567-586. https://doi.org/10.1080/19440049.2012.755644, WOS:000327813300015 (IF : 2.22)
ACLN
Chinain M, Gatti C, Darius HT. (2013). Ciguatéra: aspects physiopathologiques et cliniques. Bulletin de Veille Sanitaire Cire Antilles-Guyane, N°3/Avril 2013, 1-6.
C-INV
Chinain M, Darius HT, Gatti C, Roué M, Rossi F, Laurent D. (2013). « Integrative approach to the study of Ciguatera Fish Poisoning: the example of French Polynesia”. GEOHAB Open Science Meeting, 24-26 avril 2013, UNESCO, Paris, France
C-ACTI
Reguera B, Boisson F, Darius HT, Dechraoui-Bottein MY. (2013). Toxic micro-algal blooms: what can nuclear techniques provide for their management? In: Isotopes in Hydrology, Marine Ecosystems and Climate Change Studies, Proceedings of an International Symposium, IAEA, Monaco, 27 mars –1 avril 2011, Vol.1, 483-492.
Chinain M., Darius H.T., Gatti C., Roué M., Rossi F., Laurent D. 2013. « Integrated approach to the study of Ciguatera Fish Poisoning: the example of French Polynesia”. GEOHAB Open Science Meeting, UNESCO, Paris, France, 24-26 Avril 2013.
C-AFF
Gatti C, Darius T, Chinain M. (2013). Consommation de poissons lagonaires et ciguatéra. Conférence régionale francophone sur l’alimentation, 3-5 octobre 2013, Tahiti.
Gatti C, Darius T, Chinain M. (2013). Consommation de poissons : entre risques et bénéfices pour la santé. Conférence régionale francophone sur l’alimentation, 3-5 octobre 2013, Tahiti.
2012
ACL
Rossi F, Jullian V, Pawlowiez R, Kumar-Roiné S, Haddad M, Darius HT, Gaertner-Mazouni N, Chinain M, Laurent D. (2012). Protective effect of Heliotropium foertherianum (Boraginaceae) folk remedy and its active compound, rosmarinic acid, against a Pacific ciguatoxin. J Ethnopharmacol 143 : 33-40. . https://doi.org/10.1016/j.jep.2012.05.045 , WOS:000308678600004 (IF : 2,775).
OS
Laurent D, Kerbrat AS, Darius HT, Rossi F, Yeeting B, Haddad M, Golubic S, Pauillac S, Chinain M. (2012). Ciguatera Shellfish Poisoning, a new ecotoxicological phenomenon from cyanobacteria to human via giant clams. In: Food Chain: New Research, Jensen M.A. & Muller D.W (Eds.), Nova Publishers, Chapter I, 1-44. ISBN 978-1-61324-377-0
C-ACTI
Rossi F, Jullian V, Pawlowiez R, Haddad M, Darius HT, Chinain M, Richert L, Gaertner-Mazouni N, Laurent D. (2012). Protective effect of Heliotropium foertherianum and rosmarinic acid against Pacific ciguatoxins. 13ième Congrès International de la Société d’Ethnopharmacologie, 2-6 septembre 2012, Graz, Autriche.
C-COM
Roué M, Cruchet P, Ung A, Darius HT, Chinain M, Laurent D. (2012). Giant-clams : New Vectors of Ciguatera ? 20th Meeting of the French Society of Toxinology SFET, 10-11 Décembre 2012, Paris, France.
Roué M, Cruchet P, Ung A, Darius HT, Chinain M, Laurent D. (2012). Les bénitiers: nouveaux vecteurs de la ciguatéra? Assemblée générale du GDR Biochimar, 10-12 Décembre 2012, Gif-sur-Yvette, France.
AP
Bottein MY, Cruz L, Darius HT, Descroix F, Doucette G, Fire S, Leighfield T, Mikulski T, Sombrito E, Van Dolah F. (2012). Detection of Harmful Algal Toxins using the radioligand receptor binding assay. A manual of methods. IAEA. 50 pp.
Projets Scientifiques
- OPEX-CTX 2.0 (2020-2023)
Optimisation du protocole d’extraction/purification des ciguatoxines à partir de produits marins - DIAGNOCIG (2021-2023)
Détection des ciguatoxines dans le sang et urines des patients à des fins diagnostiques. - FLUOTRACK-CIGUATERA (2014-2017)
Evolution technologique du test ligand-récepteur pour la détection des ciguatoxines (CTXs) : vers un format haut-débit, exempt de radioactivité. - CELEX (2012-2014)
Caractérisation Eco-toxicologique des Lagons Exploités
Participation à des projets
- TRANSIENT CTX (2021-2023)
Essais de biotransformation enzymatique des ciguatoxines algales en conditions in vitro – Etude de faisabilité - CIGUAWATCH (2016 – 2023)
Mise en place d’un réseau de surveillance de la ciguatéra dans le Pacifique - GLOBALCIG (2017-2021)
Ciguatera et changement global : effets de la température, du pH et de la disponibilité en nutriments sur la croissance et la production de ciguatoxines chez Gambierdiscus. - TATOO (2018-2020)
Caractérisation taxonomique et toxinique des espèces d’Ostreopsis (dinoflagellés benthiques) associées à la ciguatéra dans les archipels de Polynésie française. - OCEASAFE-Polynésie (2018-2020)
Développement de biosenseurs pour la détection de toxines marines émergentes - CIGUAPROD (2016-2019)
« Centre de production de microalgues et de ciguatoxines » - Ciguatéra Marquises (2018)
Evaluation du risque ciguatérique suite à une alerte sanitaire à Hatiheu (Nuku Hiva, Marquises) - CARISTO-PF (2016-2018)
Gestion des risques environnementaux et sanitaires liés au développement du phytobenthos ciguatérigène en Polynésie française. - CIGUAPROD (2017)
Centre de production de microalgues et de ciguatoxines - INTEGRE (2016-2017)
Mise en place d’un système de surveillance pérenne couplant l’environnement et la santé animale dans le cadre d’une démarche participative (volet ciguatéra, Tahiti). - MOBIO (2016-2017)
Micro-algues des lagons polynésiens: nouvelles sources de molécules bio-actives? - EFFLOREX (2014-2016)
Le phytoplancton responsable des efflorescences algales dans les lagons exploités de Polynésie : étude des potentiels nutritionnel et toxique. - Ciguatera : a neglected disease in the South Pacific (2014-2016)
Ce programme financé par le Fonds Pacifique vise à renforcer la coopération régionale entre la Polynésie et la Nouvelle-Zélande, pour mieux lutter contre les impacts sanitaires et économiques de la ciguatéra dans le Pacifique sud. Les sites d’étude retenus sont la Polynésie, les îles Cook et la Nouvelle-Zélande. - BIOSEAF – Polynésie (2012-2015)
Biotoxines Marines et Sécurité Alimentaire des Filières Lagonaires en Polynésie française.
Participation à des programmes et réseaux de recherche nationaux et internationaux
- GDR Phycotox : le laboratoire des Biotoxines Marines est membre du GDR Phycotox depuis 2013
http://www.phycotox.fr/reseau/presentations-des-equipes-du-gdr-phycotox/ilm.html
